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. 2021 Feb 8;13:1759091421994351. doi: 10.1177/1759091421994351

Figure 1.

Figure 1.

The Neuroprotective Roles of Trx and Its Inducers in AD. (A) Aβ deposition induces oxidative stress (ROS), which in turn accelerates Aβ deposition and the formation of fibril Aβ. Both of Aβ deposition and ROS induction lead to compromised antioxidant activity of the cells, which further promote the AD progress. (B) Trx and its inducers plays the anti-oxidative, anti-apoptotic, anti-inflammatory and pro-survival roles in AD models.