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. Author manuscript; available in PMC: 2022 Apr 1.
Published in final edited form as: Br J Ophthalmol. 2020 Jun 3;105(4):490–495. doi: 10.1136/bjophthalmol-2020-316152

Table 3.

Diagnostic accuracy parameters as estimated in the included systematic reviews

RNFL parameters GCC/GCIPL parameters other parameters
Ahmed et al20 ► Unqualified parameter (n. 17)
 Se: 83.3 (77.2 to 88)
 Sp: 91.6 (87.8 to 94.2)
Fallon et al21 ► RNFL average (n. 50)
 Se: 0.78 (0.74 to 0.83)
 Sp: 0.91 (0.88 to 0.93)		 ► GCC average (n. 14)
 Se: 0.79 (0.71 to 0.88)
 Sp: 0.88 (0.82 to 0.94)		 ► C/D vertical ratio (n. 14)
 Se: 0.78 (0.74 to 0.83)
 Sp: 0.91 (0.88 to 0.93)
Kansal et al22 ► RNFL average (n. 119)
 AUC: 0.901 (0.877 to 0.917)		 ► GCIPL average (n. 28)
 AUC: 0.858 (0.835 to 0.880)
► RNFL inferior (n. 95)
 AUC: 0.905 (0.869 to 0.925)		 ► GCC average (n. 39)
 AUC: 0.885 (0.869 to 0.901)
Michelessi et al28 ► RNFL average (n. 57)
 Se: 0.69 (0.63 to 0.73)
 Sp: 0.94 (0.93 to 0.95)		 ► GCC/GCIPL average (n. 32)
 Se: 0.63 (0.57 to 0.70)
 Sp: 0.93 (0.91 to 0.94)		 ► C/D vertical ratio (n.15)
 Se: 0.72 (0.60 to 0.81)
 Sp: 0.94 (0.90 to 0.94)
► RNFL inferior sector (n. 45)
 Se: 0.72 (0.65 to 0.77)
 Sp: 0.93 (0.92 to 0.95)

AUC, area under the receiver operating characteristic curve; C/D, cup/disc; GCC, ganglion cell complex; GCIPL, ganglion cell layer +Inner plexiform layer; RNFL, retinal nerve fibre layer; Se, sensitivity; Sp, specificity.