Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Feb 11;40:64. doi: 10.1186/s13046-021-01858-1

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

PMC Copyright notice

Fig. 1 — Abnormal expression of ESCO2 is associated with poor prognoses in LUAD. a–c ESCO2 mRNA expression in normal lung tissues and LUAD tissues was detected using the Oncomine database. d–f ESCO2 mRNA expression in normal lung tissues and paired LUAD tissues was analyzed based on three LUAD mRNA expression profiling datasets (GSE21933, GSE10072, GSE32863). g and h Patients in the GSE50081 (g) and GSE31210 (h) datasets with high ESCO2 expression had shorter OS. (I) ESCO2 mRNA expression levels were analyzed in normal lung tissues and LUAD tissues from TCGA database. j–l Analysis of TCGA LUAD cohort showed that, compared with patients with low ESCO2 expression levels (the lowest 30%), patients with high ESCO2 mRNA expression (the highest 30%) had higher death rates, shorter disease-free survival, and shorter OS. m and n ESCO2 mRNA (m) and ESCO2 protein (n) expression levels were detected in normal lung tissues and paired LUAD tissues (n = 5)