Table 3.
Frequency of most common TEAEs (occurring in ≥10% of the population)
| Any grade (n = 23) | Grade 3/4 (n = 23) | |
|---|---|---|
| Any TEAE, n (%) | 23 (100) | 19 (82.3) |
| Fatigue | 12 (52.2) | 3 (13.0) |
| Diarrhea | 11 (47.8) | 3 (13.0) |
| Hyperglycemia | 11 (47.8) | 9 (39.1) |
| Hypertension | 10 (43.5) | 9 (39.1) |
| Nausea | 6 (26.1) | 0 |
| Neutropenia | 6 (26.1) | 3 (13.0) |
| Pruritus | 6 (26.1) | 0 |
| Anemia | 5 (21.7) | 1 (4.3) |
| Cough | 5 (21.7) | 0 |
| Pyrexia | 5 (21.7) | 1 (4.3) |
| Upper abdominal pain | 5 (21.7) | 0 |
| Constipation | 4 (17.4) | 0 |
| Pneumonia | 4 (17.4) | 3 (13.0) |
| Arthralgia | 3 (13.0) | 0 |
| Dizziness | 3 (13.0) | 0 |
| Insomnia | 3 (13.0) | 0 |
| Maculopapular rash | 3 (13.0) | 0 |
| Muscle spasms | 3 (13.0) | 1 (4.3) |
| Oropharyngeal pain | 3 (13.0) | 0 |
| Upper respiratory infection | 3 (13.0) | 1 (4.3) |
| Vomiting | 3 (13.0) | 0 |
TEAEs were coded according to the Medical Dictionary for Regulatory Activities.