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. 2021 Feb 1;45(4):8. doi: 10.3892/or.2021.7959

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Copyright: © Chen et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 6. — miR-15a-5p suppressed the proliferation, migration and invasion of BC cells by inhibiting HMGA1. (A) HMGA1 expression detection by RT-qPCR post-overexpression of both miR-15a-5p and HMGA1 in T24 and UM-UC-3 cells. (B) Cell proliferation detection by EdU experiment post overexpression of miR-15a-5p and HMGA1 in T24 and UM-UC-3 cells; magnification, ×200. (C) Cell clone formation by colony formation experiment post-overexpression of miR-15a-5p and HMGA1 in T24 and UM-UC-3 cells. (D) The change of cell migration via Transwell migration experiment post-overexpression of miR-15a-5p and HMGA1 in T24 and UM-UC-3 cells; magnification, ×200. (E) The change of cell invasion via Transwell invasion experiment post overexpression of miR-15a-5p and HMGA1 in T24 and UM-UC-3 cells; magnification, 200. **P<0.01; ***P<0.001; ^#P<0.05; ^##P<0.01.