Table 2.
Comparison of biochemical parameters among PC patients, patients with benign pancreatic diseases and healthy volunteers
| Variables | PC patients (n = 114) |
Patients with BPDs (n = 94) |
HVs (n = 120) |
p value (s) | |
|---|---|---|---|---|---|
| Median (range) | Median (range) | Median (range) | PC vs. BPDs | PC vs. HVs | |
| Total bilirubin, µmol/L | 44.8 (19.2–141.5) | 9.16 (6.3–72.8) | 7.24 (3.68–15.1) | < 0.001 | < 0.001 |
| Albumin, g/L | 31.48 (20.1–83.5) | 42 (39.7–65.4) | 51.3 (27.1–168.3) | < 0.001 | < 0.001 |
| Alanine transaminase, U/L | 42 (34.1–144) | 24.3 (24.3–59.5) | 18.8 (13.3–41) | < 0.001 | < 0.001 |
| Aspartate aminotransferase, U/L | 116.9 (62–328.4) | 37.5 (27.9–212.4) | 27.2 (18–59.6) | < 0.001 | < 0.001 |
| Alkaline phosphatase, U/L | 109.7 (39.2–247.6) | 80.4 (19.3–169.2) | 71.2 (41.5–145.2) | 0.008* | 0.005* |
| γ-glutamyl transferase, U/L | 102.3 (77.5–201.2) | 51.4 (25–110.2) | 44.7 (37.2–88.6) | 0.005* | 0.004* |
| Glucose, mmol/L | 9.3 (8.8–28.7) | 8.7 (3.4–42.6) | 4.5 (4.1–8.2) | 0.086 | < 0.001 |
| Creatinine, µmol/L | 87.3 (45.3–143.3) | 71.2 (19.3–95.5) | 64.7 (32.6–213.8) | 0.043* | 0.027* |
| Prothrombin time, sec | 17.3 (4.5–56.1) | 18.4 (8.7–92.6) | 12.6 (10.6–58) | 0.074 | 0.018* |
| Activated partial prothrombin time, sec | 44.5 (37.4–103.5) | 27.3 (10.9–90.1) | 30.5 (22.2–67.5) | < 0.001 | < 0.001 |
| D-dimer, µg/mL | 0.8 (0.4–2.3) | 0.3 (0.08–1.9) | 0.2 (0.03–1.2) | < 0.001 | < 0.001 |
BPDs, benign pancreatic diseases; HVs, healthy volunteers
*Depicts results were significant at p < 0.05