Table 2.
Sex-, age- and period-specific estimates of prevalence and incidence of Huntington disease (HD) in Navarre, for the period 1991–2017
| Number of HD cases | Prevalence | Incidence | |||||
|---|---|---|---|---|---|---|---|
| Total | Symptomatic | Asymptomatic (n)a | Total prevalent cases | Point prevalence rate per 100,000 (95% CI) | Total incident cases | Annual incidence rate per 100,000 (95% CI) | |
| Total | 80 | 61 | 19 | 65 | 63 | 0.40 (0.31, 0.50) | |
| Sex | |||||||
| Men | 38 (47%) | 26 | 12 (4) | 15 (47%) b | 4.68 (2.31, 7.05)b | 29 (46%) | 0.37 (0.25, 0.52) |
| Women | 42 (53%) | 35 | 7 | 17 (53%) b | 5.20 (2.73, 7.67)b | 34 (54%) | 0.43 (0.30, 0.59) |
| Age (years) | |||||||
| ≤ 20 | 4 | 1 | 3 (1) | 0b | 0b | 1 | 0.03 (0, 0.16) |
| 21–40 | 22 | 8 | 14 (2) | 4b | 2.64 (0.05, 5.22)b | 10 | 0.19 (0.10, 0.35) |
| 41–60 | 28 | 26 | 2 (1) | 10b | 5.11 (1.94, 8.27)b | 26 | 0.63 (0.42, 0.91) |
| > 60 | 26 | 26 | 0 | 18b | 11.53 (6.20, 16.85)b | 26 | 0.78 (0.52, 1.12) |
| Period | |||||||
| 1991–1999 | 26 | 23 | 3 (2) | 31c | 5.70 (3.69, 7.71)c | 22 | 0.46 (0.30, 0.69) |
| 2000–2008 | 28 | 21 | 7 (1) | 32d | 5.07 (3.31, 6.83)d | 21 | 0.39 (0.25, 0.59) |
| 2009–2017 | 24 | 15 | 9 (1) | 32b | 4.94 (3.23, 6.65)b | 20 | 0.35 (0.22, 0.53) |
aNumber of HD presymptomatic cases that became symptomatic throughout the study period
Point prevalence dates: b31/12/2017, c31/12/1999, d31/12/2008