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. 2021 Feb 15;18(1):184–198. doi: 10.20892/j.issn.2095-3941.2020.0012

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Copyright: © 2021, Cancer Biology & Medicine

This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY) 4.0, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.

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Patient-derived xenograft (PDX) tumor growth kinetics. (A) Illustration of non-small cell lung cancer PDX model development and characterization. (B) The scatter plot represents the time to tumor palpation (300 mm³) of the first generation (i) and passages 0–5 (ii) of 13 small cell carcinoma (SCC) PDXs and 10 adenocarcinoma (ADC) PDXs. (C) Tumor volume as a function of the days post-implantation of squamous cell carcinoma LC-00507 (i) and ADC LC-00592 (ii). Each color represents the specified generation and each curve represents a single tumor.