Table 1.
List of considerable biomarkers for COVID-19.
| S.No. | Biomarker | Normal patient | Affected patient | Ref. |
|---|---|---|---|---|
| 1 | Serum ferritin, (ng/mL) | 15.0–150.0 | 800.4 (452.9–1,451.6) | [102] |
| 2 | Cholinesterase (CHE) (kU/L) | 8–18 | 1.5–8 | [106] |
| 3 | C-reactive protein (CRP) (mg/L) | 0.0–1.0 | 57.9 (20.9–103.2) | [102] |
| 4 | Creatinine (CREA) (μmol/L) | 60–120 | 30–80 | [106] |
| 5 | Interleukin-2R, (U/mL) | 223.0–710.0 | 757.0 (528.5–1,136.3) | [102] |
| 6 | Lactate dehydrogenase (LDH) (U/L) | 140–280 | 300–600 | [106] |
| 7 | IL-6 (pg/mL) | 0·0–7.0 | 7·9 | [103] |
| 8 | IL-10 (pg/mL) | 0–9.1 | >15 | [105] |
| 9 | Cystatin C (Cys C) mg/dl | 0.6–1.3 | >1.1 | [106] |
| 10 | D-dimer (μg/mL) | 0–0.243 | 0.4 | [19] |
| 11 | Urea (mmol/L) | 2.5–7.1 | 4–22 | [106] |
| 12 | Lymphocyte count (×109/L) | 0.8–4 | <0.6 | [104] |
| 13 | Serum amyloid A (SAA) (mg/L) | 0–10 | 108.4 | [19] |
| 14 | Procalcitonin (ng/mL) | 0–0.5 | <0.1 | [104] |
| 15 |
Serum direct bilirubin (DBIL) (μmol/L) |
5.1–17 |
>8-60 |
[106] |
|
Qualitative changes in the blood profile of COVID-19 patients. (The information is adapted from the clinical studies of [107]) | ||||
| Hematologic | WBC count Neutrophil count |
Increases | ||
| Lymphocyte count Platelet count Eosinophil count Hemoglobin |
Decreases | |||
| Biochemical | Alanine aminotransferase Aspartate aminotransferase Total bilirubin Blood urea nitrogen Creatinine Creatine kinase Lactate dehydrogenase Myoglobin Creatine kinase-MB Cardiac Troponin I |
Increases | ||
| Albumin | Decreases | |||
| Coagulation | Prothrombin time D-dimer |
Increases | ||
| Inflammatory biomarkers | Erythrocyte sedimentation rate CRP Serum-ferritin PCT IL-2R IL-6 IL-8 IL-10 |
Increases | ||