TABLE 2.
CAP | COVID-19 | |
Severity | IDSA/ATS severe CAP [11] | Severe acute respiratory failure# |
Timing | First 24 h | First 24 h |
Type of steroids and dosage | Prednisone (50 mg daily) Methylprednisolone (40–80 mg daily) Dexamethasone (5 mg daily) |
Dexamethasone (6 mg daily) Hydrocortisone (200 mg daily) |
Duration | 5–8 days | 7 days |
Outcome | Decrease treatment failure and mortality | Decrease mortality |
Harms | Increased readmission in one study | CAPA? |
IDSA: Infectious Diseases Society of America; ATS: American Thoracic Society; CAPA: COVID-19-associated pulmonary aspergillosis. #: as defined in the RECOVERY trial [58].