Fig 3. Association signals with T2D in the broad region of chr 6.
The top panel depicts association signals from admixture mapping on 3,428 unrelated individuals. The middle panel depicts the single variant association result of the same region, using linear mixed model on all 3,940 individuals with genotype dosages imputed from 1000 Genomes Project. The bottom panel shows the corresponding genomic coordinates and nearby genes. Highlighted region at the bottom indicates the signal region as defined in Table 2. LD between rs370140172 and other variants in the region, as shown in the color legend, was r2 calculated in sample using the imputed genotypes.