Table 3. Association of global ancestry with measures of fat distribution or fat composition among Native Hawaiians.
Combined | Male | Female | ||||
---|---|---|---|---|---|---|
Estimate (s.e.) | P | Estimate (s.e.) | P | Estimate (s.e.) | P | |
Subcutaneous Fat | ||||||
Intercept | -0.39 (0.25) | 0.11 | -0.58 (0.35) | 0.10 | -0.25 (0.37) | 0.51 |
PNS | 1.30 (0.28) | 4.88x10-6 | 1.52 (0.4) | 2.29x10-4 | 1.14 (0.4) | 0.0052 |
EAS | -0.14 (0.22) | 0.54 | 0.050 (0.33) | 0.88 | -0.28 (0.32) | 0.38 |
AFR | 3.16 (1.80) | 0.080 | 5.45 (3.62) | 0.13 | 2.46 (2.12) | 0.25 |
Total fat mass | -0.0044 (0.0081) | 0.59 | -0.0033 (0.013) | 0.80 | -0.0056 (0.011) | 0.62 |
Visceral Fat | ||||||
Intercept | -0.26 (0.26) | 0.31 | -0.11 (0.37) | 0.77 | -0.48 (0.38) | 0.20 |
PNS | 0.71 (0.29) | 0.014 | 0.55 (0.42) | 0.19 | 0.98 (0.4) | 0.016 |
EAS | -0.29 (0.23) | 0.21 | -0.092 (0.35) | 0.79 | -0.36 (0.32) | 0.27 |
AFR | 3.45 (1.85) | 0.064 | 6.54 (3.82) | 0.089 | 2.45 (2.13) | 0.25 |
Total fat mass | 0.0012 (0.0083) | 0.89 | -0.0082 (0.013) | 0.54 | 0.0073 (0.011) | 0.52 |
Lean-to-Fat Mass Ratio | ||||||
Intercept | 0.11 (0.18) | 0.55 | 0.49 (0.28) | 0.079 | -0.23 (0.25) | 0.37 |
PNS | -0.087 (0.29) | 0.76 | -0.64 (0.42) | 0.13 | 0.40 (0.39) | 0.31 |
EAS | -0.28 (0.24) | 0.24 | -0.77 (0.35) | 0.030 | 0.15 (0.33) | 0.64 |
AFR | 0.86 (1.95) | 0.66 | 0.55 (4.21) | 0.90 | 1.02 (2.21) | 0.64 |
N = 280, 280, and 294 for analysis on subcutaneous fat, visceral fat, and lean-to-fat mass ratio, respectively. In sex-stratified analysis, N = 128, 128, and 136 males for analysis on subcutaneous fat, visceral fat, and lean-to-fat mass ratio, respectively; N = 152, 152, and 158 females for analysis on subcutaneous fat, visceral fat, and lean-to-fat mass ratio, respectively. Subcutaneous and visceral fats are in units of sample standard deviation (Methods)