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. 2021 Feb 11;17(2):e1009273. doi: 10.1371/journal.pgen.1009273

Table 3. Association of global ancestry with measures of fat distribution or fat composition among Native Hawaiians.

Combined Male Female
Estimate (s.e.) P Estimate (s.e.) P Estimate (s.e.) P
Subcutaneous Fat
Intercept -0.39 (0.25) 0.11 -0.58 (0.35) 0.10 -0.25 (0.37) 0.51
PNS 1.30 (0.28) 4.88x10-6 1.52 (0.4) 2.29x10-4 1.14 (0.4) 0.0052
EAS -0.14 (0.22) 0.54 0.050 (0.33) 0.88 -0.28 (0.32) 0.38
AFR 3.16 (1.80) 0.080 5.45 (3.62) 0.13 2.46 (2.12) 0.25
Total fat mass -0.0044 (0.0081) 0.59 -0.0033 (0.013) 0.80 -0.0056 (0.011) 0.62
Visceral Fat
Intercept -0.26 (0.26) 0.31 -0.11 (0.37) 0.77 -0.48 (0.38) 0.20
PNS 0.71 (0.29) 0.014 0.55 (0.42) 0.19 0.98 (0.4) 0.016
EAS -0.29 (0.23) 0.21 -0.092 (0.35) 0.79 -0.36 (0.32) 0.27
AFR 3.45 (1.85) 0.064 6.54 (3.82) 0.089 2.45 (2.13) 0.25
Total fat mass 0.0012 (0.0083) 0.89 -0.0082 (0.013) 0.54 0.0073 (0.011) 0.52
Lean-to-Fat Mass Ratio
Intercept 0.11 (0.18) 0.55 0.49 (0.28) 0.079 -0.23 (0.25) 0.37
PNS -0.087 (0.29) 0.76 -0.64 (0.42) 0.13 0.40 (0.39) 0.31
EAS -0.28 (0.24) 0.24 -0.77 (0.35) 0.030 0.15 (0.33) 0.64
AFR 0.86 (1.95) 0.66 0.55 (4.21) 0.90 1.02 (2.21) 0.64

N = 280, 280, and 294 for analysis on subcutaneous fat, visceral fat, and lean-to-fat mass ratio, respectively. In sex-stratified analysis, N = 128, 128, and 136 males for analysis on subcutaneous fat, visceral fat, and lean-to-fat mass ratio, respectively; N = 152, 152, and 158 females for analysis on subcutaneous fat, visceral fat, and lean-to-fat mass ratio, respectively. Subcutaneous and visceral fats are in units of sample standard deviation (Methods)