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. 2021 Feb 11;16(2):e0246586. doi: 10.1371/journal.pone.0246586

Table 3. Risk indicators associated with COVID-19 and COVID-19-related clinical phenotypes in dentists.

Laboratory-confirmed COVID-19 vs tested negative or not tested COVID-19-related clinical phenotypes vs not
Univariable OR (95% CI, p-value) Multivariable OR (95% CI, p-value) Univariable OR (95% CI, p-value) Multivariable OR (95% CI, p-value)
Demographic data
Age (>44 years) 1.04 (0.66–1.66, p = 0.855) - 0.77 (0.64–0.91, p = 0.003) 0.86 (0.70–1.04, p = 0.120)
Male gender 1.17 (0.75–1.83, p = 0.479) - 0.74 (0.62–0.89, p = 0.001) 0.74 (0.61–0.89, p = 0.002)
≥ 1 child 0.72 (0.45–1.14, p = 0.166) 0.66 (0.40–1.05, p = 0.081) 0.96 (0.81–1.14, p = 0.660) -
Medical conditions
Current pregnancy 1.35 (0.22–4.41, p = 0.676) - 0.91 (0.46–1.67, p = 0.786) -
Current smoking 0.99 (0.41–2.03, p = 0.986) - 1.05 (0.78–1.40, p = 0.740) -
Comorbidities
    Allergies 3.64 (0.58–12.37, p = 0.081) 4.61 (0.72–16.52, p = 0.044) 1.66 (0.66–3.67, p = 0.241) -
    Diabetes 0.75 (0.04–3.45, p = 0.774) - 0.73 (0.32–1.44, p = 0.400) -
    Hypertension 1.65 (0.72–3.26, p = 0.187) - 0.89 (0.62–1.26, p = 0.536) -
    Cardiopathies 0.87 (0.14–2.82, p = 0.853) - 0.87 (0.49–1.44, p = 0.603) -
    COPD 0.66 (0.11–2.14, p = 0.571) - 1.61 (1.08–2.35, p = 0.016) 1.59 (1.04–2.36, p = 0.027)
    CKD 6.62 (1.04–23.80, p = 0.013) 6.52 (0.95–26.44, p = 0.021) 1.62 (0.46–4.54, p = 0.395) -
    Malignancies 0.56 (0.03–2.55, p = 0.564) - 0.60 (0.28–1.14, p = 0.150) -
    Obesity 2.94 (1.01–6.76, p = 0.023) 3.13 (1.06–7.46, p = 0.019) 1.12 (0.63–1.88, p = 0.678) -
    ID 1.13 (0.06–5.26, p = 0.906) - 1.54 (0.72–2.99, p = 0.229) -
    Other 1.14 (0.28–3.10, p = 0.826) - 1.00 (0.61–1.57, p = 0.999) -
Clinical practice
Specialty
    General practice 0.74 (0.44–1.33, p = 0.289) - 0.74 (0.59–0.92, p = 0.006) 0.82 (0.65–1.04, p = 0.099)
    Endodontics 0.24 (0.04–0.78, p = 0.049) 0.21 (0.04–0.69, p = 0.033) 0.88 (0.65–1.18, p = 0.411) -
    Oral surgery 1.20 (0.64–2.09, p = 0.537) - 1.18 (0.93–1.47, p = 0.163) -
    Orthodontics 0.48 (0.15–1.16, p = 0.154) 0.39 (0.12–0.95, p = 0.068) 0.98 (0.73–1.29, p = 0.871) -
    Pediatric dentistry 0.52 (0.13–1.39, p = 0.263) - 1.43 (1.05–1.92, p = 0.019) -
    Restaurative dentistry 0.26 (0.04–0.84, p = 0.063) - 0.92 (0.67–1.24, p = 0.607) -
    Periodontology 0.88 (0.44–1.61, p = 0.707) - 1.37 (1.09–1.70, p = 0.005) 1.35 (1.06–1.70, p = 0.014)
    Prosthodontics 0.84 (0.41–1.57, p = 0.618) - 1.02 (0.80–1.29, p = 0.857) -
    Implantology 2.00 (0.69–4.55, p = 0.142) - 1.38 (0.88–2.09, p = 0.139) -
    Gnathology 2.01 (0.48–5.52, p = 0.246) - 0.88 (0.44–1.59, p = 0.684) -
Private practice 0.49 (0.27–1.00, p = 0.033) - 0.76 (0.57–1.04, p = 0.074) -
Working in group practice 1.74 (0.98–2.93, p = 0.046) - 1.16 (0.91–1.47, p = 0.214) -
Number of staff
    Medical (>2) 1.40 (0.89–2.19, p = 0.143) - 1.20 (1.01–1.42, p = 0.034) -
    Non-medical (>2) 1.53 (0.98–2.43, p = 0.065) 1.58 (1.00–2.54, p = 0.054) 1.29 (1.08–1.53, p = 0.004) 1.23 (1.02–1.49, p = 0.029)
Taking public transportation 1.77 (0.95–3.09, p = 0.055) - 1.62 (1.27–2.06, p<0.001) 1.49 (1.15–1.93, p = 0.002)
    Before lockdown 2.03 (1.09–3.55, p = 0.018) 1.86 (0.97–3.33, p = 0.046) 1.58 (1.22–2.03, p<0.001) -
    After lockdown 0.93 (0.23–2.52, p = 0.900) - 1.67 (1.14–2.40, p = 0.007) -
Changes after lockdown
Private sphere
    Household size increase 0.65 (0.30–1.23, p = 0.219) - 0.68 (0.53–0.88, p = 0.003) 0.77 (0.58–1.00, p = 0.057)
    Household size decrease 1.04 (0.36–2.35, p = 0.935) - 1.38 (0.99–1.89, p = 0.053) 1.34 (0.94–1.87, p = 0.093)
    Relocation 0.60 (0.10–1.92, p = 0.477) - 1.53 (1.03–2.21, p = 0.027) -
    Other 3.40 (0.55–11.52, p = 0.097) - 2.49 (1.13–5.11, p = 0.017) 2.19 (0.92–4.85, p = 0.061)
Work environment
    No change 2.26 (1.12–4.16, p = 0.014) - 1.57 (1.16–2.11, p = 0.003) -
    Work rhythm 0.66 (0.39–1.08, p = 0.108) 0.58 (0.34–0.96, p = 0.039) 0.56 (0.46–0.68, p<0.001) 0.51 (0.41–0.63, p<0.001)
    Clinical practice 0.33 (0.21–0.52, p<0.001) 0.32 (0.20–0.51, p<0.001) 0.74 (0.61–0.88, p = 0.001) 0.73 (0.61–0.89, p = 0.002)
    Reduce number of medical staff 1.00 (0.54–1.71, p = 0.992) - 0.87 (0.69–1.08, p = 0.219) -
    Reduce number of paramedical staff 0.90 (0.55–1.43, p = 0.651) - 0.74 (0.61–0.89, p = 0.001) -
    Reduce number of administrative staff 1.24 (0.73–2.04, p = 0.409) - 0.84 (0.68–1.04, p = 0.120) -
    Work stopping 2.99 (1.23–6.19, p = 0.007) - 1.86 (1.23–2.75, p = 0.002) -

OR = odds ratio; 95% CI = 95% confident interval. COPD: chronic obstructive pulmonary disease; CKD: chronic kidney disease; ID: immunodeficiencies.