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. 2021 Feb 11;16(2):e0246463. doi: 10.1371/journal.pone.0246463

Table 1. Characteristics of the studies included in this meta-analysis.

Authors/Year of publication Country Male (%) Age Birth Weight (g) Diazoxide (mg/(kg · day)] Number of patients Study design Follow-up Outcomes assessed
Meissner/2003 [12] Germany 52.6 1 D−17 Y 3670 15 114 Retrospective cohort 6.6Y Respond to diazoxide
Hu/2012 [13] China 68.2 1 D−2 Y 2200−5100 5−15 44 Retrospective cohort NA Respond to diazoxide, Fluid retention, Gastrointestinal reaction, Hypertrichosis
Wang/2017 [14] China 55.1 NA 1900−5800 NA 140 Retrospective case NA Respond to diazoxide
Fukutomi/2018 [15] Japan 61.2 0 M−15 Y NA 0.3−17.4 384 Special survey 7Y Respond to diazoxide, Pulmonary hypertension, Edema, Thrombocytopenia, Fluid retention, Gastrointestinal reaction, Hypertrichosis
Herrera/2018 [16] USA 56.3 8−161 D 2350−3700 10−15 295 Retrospective cohort NA Neuthropenia, Pulmonary hypertension, Edema, Thrombocytopenia
Thornton/2019 [17] USA 58.8 1 D−17 Y 580−6600 2−12 165 Retrospective cohort NA Respond to diazoxide, Neuthropenia, Pulmonary hypertension

D: Day; Y: Year; NA: Not available.