Table 1. Characteristics of the studies included in this meta-analysis.
Authors/Year of publication | Country | Male (%) | Age | Birth Weight (g) | Diazoxide (mg/(kg · day)] | Number of patients | Study design | Follow-up | Outcomes assessed |
---|---|---|---|---|---|---|---|---|---|
Meissner/2003 [12] | Germany | 52.6 | 1 D−17 Y | 3670 | 15 | 114 | Retrospective cohort | 6.6Y | Respond to diazoxide |
Hu/2012 [13] | China | 68.2 | 1 D−2 Y | 2200−5100 | 5−15 | 44 | Retrospective cohort | NA | Respond to diazoxide, Fluid retention, Gastrointestinal reaction, Hypertrichosis |
Wang/2017 [14] | China | 55.1 | NA | 1900−5800 | NA | 140 | Retrospective case | NA | Respond to diazoxide |
Fukutomi/2018 [15] | Japan | 61.2 | 0 M−15 Y | NA | 0.3−17.4 | 384 | Special survey | 7Y | Respond to diazoxide, Pulmonary hypertension, Edema, Thrombocytopenia, Fluid retention, Gastrointestinal reaction, Hypertrichosis |
Herrera/2018 [16] | USA | 56.3 | 8−161 D | 2350−3700 | 10−15 | 295 | Retrospective cohort | NA | Neuthropenia, Pulmonary hypertension, Edema, Thrombocytopenia |
Thornton/2019 [17] | USA | 58.8 | 1 D−17 Y | 580−6600 | 2−12 | 165 | Retrospective cohort | NA | Respond to diazoxide, Neuthropenia, Pulmonary hypertension |
D: Day; Y: Year; NA: Not available.