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. 2021 Feb 11;16(2):e0246318. doi: 10.1371/journal.pone.0246318

Table 1. COVID-19 ICU study regions, ICU admitted and IMV patient number and demographics, and study quality assessement.

Reference ID (First author, publication month 2020) Number of patients Mean age ± SD Gender (male) [n (%)] Overall quality assessment
ICU admitted IMV patients in ICU
China
Bi/April [12] 19 18 (30–70)a 14/19 (74) Good
Cao/May [28] 18 14 NM NM Good
Du/April [27] 51 33 68.4±9.7 34/51 (71) Good
Feng/April [14] 29 22 64±13.4 71/114 (62) Good
Guan/February [29] 55 25 63 (53–71)b NM Good
Huang/January [32] 13 4 49(41–61)b 11/13 (85) Good
Lapidus/April [16] 59 40 62(52–70)b 38/59 (64) Fair
Lei/April [30] 15 ---- 55(44–74)b 5/15 (33) Fair
Wang/April [33] 344 100 64 (52–72)b 179/344 (52) Good
Xu/March [21] 45 20 56.7 + 15.4 29/45 (64) Good
Yang/February [31] 52 22 59·7± 13.3 35/52 (67) Good
Zheng/April [22] 34 15 66(58–76)b 23/34 (68) Fair
Zhou/March [20] 50 32 NM NM Good
USA
Arentz/March [8] 21 15 70(43–92)a 11/21 (52) Fair
Argenziano/April [9] 231 215 62.2±14.7 156/231 (68) Good
Auld/April [10] 217 165 64(54–73)b 119/217 (55) Fair
Bhatraju/March [11] 24 ---- 64±18 15/24 (63) Good
Goyal/May [26] ---- 130 64.5 (51.7–73.6)b 92/130 (71) Fair
Myers/April [17] 113 103 63 (53–73)b 74/113 (66) Good
Paranjpe/April [25] 385 ---- NM NM Good
Richardson/April [18] 1281 1151 63 (52–75)b 3437/5700(60) Good
Ziehr/April [23] 66 66 58 (23–87)b 43/65 (65) Good
UK
ICNARC/May [24] 7542 4522/6880 59.3± 12.5 5389/ 7538 (72) Good
Docherty/April [34] 1914/11185 497 72(57–82) NM Fair
Mexico
Valente-Acosta/May [35] 33 12 60.6± 12.68 23/33 (70) Good
Italy
Grasselli/April [15] 1591 1150 63 (56–70)b 1304/1591 (82) Good
Spain
Borobia/May [13] 237 ---- 64(54–71)b 57/75 (76) Good
France
Simonnet/April [19] 124 ---- 60 (51–70)b 90/124 (73) Good

Studies based on reporting region and identified by first author and 2020 publication month, the number of ICU admitted and IMV patients in ICU and their age and sex as reported per study; and overall quality assessement of the studies by the NIH quality assessment tool [2]. Abbreviations: NM = Not mentioned

a = Data range

b = Data are reported as median (IQR).