. 2021 Feb 11;16(2):e0246824. doi: 10.1371/journal.pone.0246824

Table 2. Association between physical health status in the past 14 days and the psychological impact of the 2019 coronavirus disease (COVID-19) outbreak as well as adverse mental health status during the epidemic (N = 4479).

Variable	Impact of Event			Stress			Anxiety			Depression
Variable	R²	AR²	B (95%CI)	R²	AR²	B (95%CI)	R²	AR²	B (95%CI)	R²	AR²	B (95%CI)
Prolonged or Recuring Fever
Yes	0.001	0.001	0.10(-0.01 to 0.21)	<0.001	<0.001	0.004(-0.09 to 0.09)	<0.001	<0.001	0.03(-0.09 to 0.16)	<0.001	<0.001	0.08(-0.03 to 0.19)
No			Reference			Reference			Reference			Reference
Chills or Rigors
Yes	0.001	<0.001	0.09(-0.02 to 0.20)	0.001	0.001	-0.11^*(-0.20 to- 0.02)	0.001	0.001	-0.14^*(-0.26 to -0.01)	<0.001	<0.001	-0.08(-0.19 to 0.04)
No			Reference			Reference			Reference			Reference
Headache
Yes	<0.001	<0.001	0.02(-0.07 to 0.11)	0.002	0.002	0.11^**(0.04 to 0.19)	0.002	0.002	0.15^**(0.05 to 0.25)	0.002	0.001	0.13^**(0.03to 0.22)
No			Reference			Reference			Reference			Reference
Myalgia
Yes	0.003	0.003	0.18^***(0.08 to 0.28)	<0.001	<0.001	0.03(-0.06 to 0.11)	<0.001	<0.001	0.08(-0.03 to 0.19)	<0.001	<0.001	0.03(-0.07 to 0.13)
No			Reference			Reference			Reference			Reference
Cough
Yes	0.004	0.003	0.19^***(0.10 to 0.28)	<0.001	<0.001	0.04(-0.04 to 0.12)	0.001	0.001	0.12^*(0.02 to 0.23)	<0.001	<0.001	0.07(-0.03 to 0.16)
No			Reference			Reference			Reference			Reference
Breathing Difficulties
Yes	0.001	<0.001	0.10(-0.01 to 0.21)	<0.001	<0.001	0.02(-0.07 to 0.11)	<0.001	<0.001	0.05(-0.07 to 0.18)	<0.001	<0.001	0.08(-0.04 to 0.19)
No			Reference			Reference			Reference			Reference
Dizziness
Yes	0.003	0.003	0.20^***(0.10 to 0.30)	<0.001	<0.001	-0.01(-0.09 to 0.08)	<0.001	<0.001	0.02(-0.10 to 0.13)	<0.001	<0.001	0.01(-0.10 to 0.11)
No			Reference			Reference			Reference			Reference
Rhinitis
Yes	0.002	0.002	0.14^**(0.04 to 0.24)	0.003	0.003	-0.16^***(-0.24 to- 0.08)	0.001	0.001	-0.14^*(-0.25 to -0.03)	0.001	0.001	-0.12^*(-0.22 to- 0.02)
No			Reference			Reference			Reference			Reference
Sore Throat
Yes	0.002	0.002	0.15^**(0.05to 0.24)	<0.001	<0.001	0.06(-0.02 to 0.14)	0.001	0.001	0.14^*(0.03 to 0.25)	<0.001	<0.001	0.07(-0.03 to 0.17)
No			Reference			Reference			Reference			Reference
Recurrent fever with cough or breathing difficulties
Yes	0.003	0.003	0.65^***(0.31 to 1.00)	0.016	0.015	1.22^***(0.93 to 1.50)	0.020	0.019	1.84^***(1.46 to 2.22)	0.018	0.017	1.58^***(1.23 to 1.93)
No			Reference			Reference			Reference			Reference
Nausea, vomiting and diarrhoea
Yes	<0.001	<0.001	0.01(-0.10 to 0.13)	0.002	0.001	-0.13^**(-0.23 to -0.04)	0.002	0.002	-0.19^**(-0.31 to -0.06)	0.001	<0.001	-0.10(-0.22 to 0.02)
No			Reference			Reference			Reference			Reference
Have you seen a doctor or visited a GP?
Yes	0.003	0.003	0.25^***(0.11 to 0.39)	0.023	0.023	0.59^***(0.48 to 0.71)	0.022	0.022	0.79^***(0.63 to 0.94)	0.022	0.022	0.71^***(0.57 to 0.85)
No			Reference			Reference			Reference			Reference
Hospitalisation
Yes	0.006	0.006	0.61^***(0.38 to 0.84)	0.034	0.034	1.23^***(1.04 to 1.42)	0.041	0.040	1.81^***(1.55 to 2.06)	0.038	0.038	1.59^***(1.36 to1.82)
No			Reference			Reference			Reference			Reference
Have you been tested for COVID-19
Yes	0.005	0.004	0.45^***(0.26 to 0.65)	0.024	0.024	0.87^***(0.70 to 1.03)	0.025	0.025	1.19^***(0.98 to 1.41)	0.027	0.026	1.11^***(0.91 to 1.30)
No			Reference			Reference			Reference			Reference
Have you been quarantined
Yes	0.004	0.004	0.41^***(0.23 to 0.60)	0.015	0.015	0.65^***(0.50 to 0.80)	0.014	0.013	0.83^***(0.63 to 1.04)	0.016	0.016	0.82^***(0.63 to 1.01)
No			Reference			Reference			Reference			Reference
Self-assessment of health status
Very bad or bad	0.026	0.026	0.48^*(0.12 to 0.84)	0.093	0.092	1.23^***(0.94 to 1.51)	0.113	0.113	1.41^***(1.02 to 1.80)	0.108	0.108	1.40^***(1.05 to 1.75)
Normal	0.026	0.026	0.55^***(0.45 to 0.65)			0.82^***(0.74 to 0.90)			1.27^***(1.16 to 1.37)			1.11^***(1.01to 1.21)
Good or very good			Reference			Reference			Reference			Reference
History of chronic disease
Yes	<0.001	<0.001	0.07(-0.03 to 0.18)	0.011	0.010	0.31^***(0.22 to 0.39)	0.015	0.014	0.49^***(0.37 to 0.60)	0.008	0.008	0.33^***(0.22 to 0.43)
No			Reference			Reference			Reference			Reference
Health insurance
Yes	0.017	0.016	0.34^***(0.26 to 0.41)	<0.001	<0.001	-0.02(-0.08 to 0.05)	0.001	0.001	0.08(-0.004 to 0.17)	<0.001	<0.001	-0.02(-0.10 to 0.05)
No			Reference			Reference			Reference			Reference

* p<0.05;

** p<0.01,

*** p<0.001