Table 1. Percentages of the experimentally determined poses determined as the top scoring pose, in the top three, five, 25%, and 50% of scoring poses, among poses resulting from molecular docking.

Docking was performed using rDock with the dock desolvation potential with the native conformation of a ligand as an input.

	percentage of complexes, for which the reference ligand is scored:
	as the top scoring pose	in top three scoring poses	in top five scoring poses	in the first quartile	in the second quartile
rDock (dock)	0.0%	0.0%	0.0%	3.4%	3.4%
rDock (dock_solv)	13.8%	13.8%	17.2%	17.2%	20.7%
LigandRNA (2013)	0.0%	3.4%	6.9%	44.8%	58.6%
LigandRNA (updated)	0.0%	0.0%	3.4%	44.8%	58.6%
AnnapuRNA DL (2013)	34.5%	44.8%	48.3%	72.4%	79.3%
AnnapuRNA DL (2016)	37.9%	41.4%	48.3%	69.0%	79.3%
AnnapuRNA kNN (2013)	34.5%	41.4%	48.3%	72.4%	75.9%
AnnapuRNA kNN (2016)	31.0%	44.8%	48.3%	72.4%	82.8%