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(A-C) X-rays at age 4 days (A), 2 months (B) and 8 months (C) show fractures with callus formation, gracile and thin ribs with fractures, platyspondyly and severe hypomineralization. (D) Skull X-ray at age 10 months shows severe thinning and Wormian bones. (E-F) X-rays at 3 years of age show crowding of the ribs, scoliosis and femora with ‘Zebra lines’ following regular pamidronate infusions.
