Fig 5. Dynamics of HTLV-1-infected clones in a patient who received Tax peptide-pulsed dendritic cell vaccine.

(A) Proviral load (%PBMCs) before and after treatment with a Tax peptide-pulsed dendritic cell vaccine. The time of vaccination is indicated by the arrows. (B) Dynamics of the abundance of infected clones in this treated patient. The top 20 abundant clones before treatment are shown in red. (C) The frequency of the infected clones that have tax nonsense mutation (W56*, W248*) at each observation point is shown in left panel. The frequency of type 2 provirus (lacking 5’LTR and internal regions of provirus) is shown in the right panel.