Table A.3.

Results of Liver Function Tests (n = 26).

Parameter (normal reference range)	Before hypoxoside tablets, mean ± sd [95% CI]	After hypoxoside tablets, mean ± sd [95% CI]	p value*
•AST (<42 U/ L)	27.8 ± 5.8 [25.3 – 30.2]	29.0 ± 7.8 [25.7 – 32.2]	0.84
ALT (< 42 U/ L)	26.9 ± 7.6 [23.8 – 30.0]	23.9 ± 13.1 [18.6 – 29.2]	0.15
ALP (20 – 130 U/L)	109.8 ± 52.4 [88.6 – 131.0]	84.8 ± 35.9 [70.3 – 99.3]	0.09
Total protein (60 – 81 U/ L)	74.5 ± 7.6 [71.5 – 77.6]	77.6 ± 6.0 [75.2 – 80.0]	0.04
Albumin (35 – 50 g/ L)	42.9 ± 5.7 [40.5 – 45.2]	44.3 ± 6.8 [41.5 – 47.0]	0.40
GGT (15 – 85 U/ L)	39.3 ± 17.5 [32.2 – 46.3]	40.9 ± 14.3 [35.1 – 46.6]	0.62
Total bilirubin (3 – 21 μmol/ L)	6.5 ± 3.6 [5.0 – 8.0]	6.8 ± 2.5 [5.8 – 7.8]	0.75
Direct (conjugated) bilirubin (2.1 – 5.1 μmol/ L)	3.2 ± 1.1 [2.7 – 3.6]	3.2± 1.1 [2.7 – 3.6]	0.96

^•Outliers at baseline excluded from analysis (n=2)

^*p-value obtained from paired t-test

sd – standard deviation

CI – confidence interval