Table 2.

Performance of SVR models (R² statistic) predicting biomarker measures.

Biomarker	SVR R2 (Original)	SVR R2 (Partial CVH)	SVR R2 (Partial WMH)
Aβ42	.028**	.008	.001
NfL	.040*	.040^	.011
HCV	.231***	.195***	.080***
AD Signature	.159***	.089***	.022*

Performance is presented for original models, as well as after statistically controlling for cardiovascular health composite (CVH) and white matter hyperintensity (WMH) values in BOLD SD estimates. Aβ42 = CSF Amyloid β peptide 42, NfL = CSF neurofilament light, HCV = adjusted hippocampal volume, AD Signature = Alzheimer Disease cortical thickness signature

^{^}p < .10;

^*p < .05;

^**p < .01;

^***p < .001