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. Author manuscript; available in PMC: 2021 Sep 1.
Published in final edited form as: Curr Opin HIV AIDS. 2020 Sep;15(5):267–274. doi: 10.1097/COH.0000000000000639

Figure 1.

Figure 1.

Conservation of glycans and the glycan shield in M-group Envs.

(A) Distribution of unique (i.e. per protomer) glycans in an alignment of ~4,800 M-group Envs (2018 Filtered Web alignment from the Los Alamos HIV Database, www.hiv.lanl.gov). Hypervariable loop glycans are excluded. (B) Distribution of glycan frequency in M-group Envs. Hypervariable loop glycans and glycans with <10% frequency are excluded. (C) Structural mapping of glycan sites in (B). PDB: 5FYJ [1]. (D) Conservation of glycan shielding in M-group using the calculations from Wagh et al. [5*].

Original.