Table 3.
Variable | All patients | Pure GGO | Consolidation | Nodules | Fibrous stripes | Mixed | p Value | |
---|---|---|---|---|---|---|---|---|
Stage I | 361 | 103 | 47 | 83 | 19 | 109 | ||
Stable | 43 (11.9) | 11 (10.7) | 8 (17.0) | 14 (16.9) | 3 (15.8) | 7 (6.4) | .155 | |
Progression | 161 (44.6) | 53 (51.5) | 24 (51.1) | 12 (14.5) | 8 (42.1) | 64 (58.7) | .000 | |
Density | Scope | |||||||
↑ | – | 22 (13.7) | 4 (7.5) | 3 (12.5) | 1 (8.3) | 0 (0) | 14 (21.9) | .140 |
– | ↑ | 32 (19.9) | 19 (35.8) | 2 (8.3) | 1 (8.3) | 3 (37.5) | 7 (10.9) | .003 |
↑ | ↑ | 45 (28.0) | 7 (13.2) | 11 (45.8) | 1 (8.3) | 0 (0) | 26 (40.6) | .000 |
Appearance of new lesions | 62 (38.5) | 23 (43.4) | 8 (33.3) | 9 (75.0) | 5 (62.5) | 17 (26.6) | .008 | |
Disappearance in one area but appearance at another site | 76 (21.1) | 17 (16.5) | 3 (6.4) | 31 (37.3) | 2 (10.5) | 23 (21.1) | .000 | |
Absorption | 81 (22.4) | 22 (21.4) | 12 (25.5) | 26 (31.3) | 6 (31.6) | 15 (13.8) | .045 | |
Density | Scope | |||||||
↓ | – | 21 (25.9) | 5 (22.7) | 4 (33.3) | 4 (15.4) | 1 (16.7) | 7 (46.7) | .232 |
– | ↓ | 21 (25.9) | 14 (63.6) | 2 (16.7) | 0 (0) | 3 (50.0) | 2 (13.3) | .000 |
↓ | ↓ | 23 (28.4) | 3 (13.6) | 6 (50.0) | 7 (26.9) | 2 (33.3) | 5 (33.3) | .249 |
↓ | slight ↑ | 16 (19.8) | 0 (0) | 0 (0) | 15 (93.8) | 0 (0) | 1 (6.7) | .000 |
Appearance of pleural effusion | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | ||
Appearance of fibrosis | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | ||
Medium TSS | 4 (1–8) | 4 (1–6) | 5 (2–6) | 3 (1–4) | 3 (1–5) | 5 (3–8) | .000 | |
Stage II | ||||||||
Stable | 31 (8.6) | 7 (6.8) | 5 (10.6) | 11 (13.3) | 2 (10.5) | 6 (5.5) | .356 | |
Progression | 95 (26.3) | 27 (26.2) | 13 (27.7) | 9 (10.8) | 5 (26.3) | 41 (37.6) | .002 | |
Density | Scope | |||||||
↑ | – | 13 (13.7) | 2 (7.4) | 2 (15.4) | 0 (0) | 0 (0) | 9 (22.0) | .238 |
– | ↑ | 22 (23.2) | 13 (48.1) | 1 (7.7) | 1 (11.1) | 3 (60.0) | 4 (9.8) | .001 |
↑ | ↑ | 29 (30.5) | 1 (3.7) | 7 (53.8) | 1 (11.1) | 0 (0) | 20 (48.8) | .000 |
Appearance of new lesions | 31 (32.6) | 11 (40.7) | 3 (23.1) | 7 (77.8) | 2 (40.0) | 8 (19.5) | .011 | |
Disappearance in one area but appearance at another site | 59 (16.3) | 13 (12.6) | 2 (4.3) | 27 (32.5) | 1 (5.3) | 16 (14.7) | .000 | |
Absorption | 176 (48.8) | 56 (54.4) | 27 (57.4) | 36 (43.4) | 11 (57.9) | 46 (42.2) | .185 | |
Density | Scope | |||||||
↓ | – | 50 (28.4) | 11 (19.6) | 9 (33.3) | 11 (30.6) | 1 (9.1) | 18 (39.1) | .129 |
– | ↓ | 41 (23.3) | 29 (51.8) | 4 (14.8) | 0 (0) | 5 (45.5) | 3 (6.5) | .000 |
↓ | ↓ | 71 (40.3) | 16 (28.6) | 14 (51.9) | 13 (36.1) | 5 (45.5) | 23 (50.0) | .142 |
↓ | slight ↑ | 14 (8.0) | 0 (0) | 0 (0) | 12 (85.7) | 0 (0) | 2 (4.3) | .000 |
Appearance of pleural effusion | 2 (0.6) | 0 (0) | 1 (2.1) | 0 (0) | 0 (0) | 1 (0.9) | .475 | |
Appearance of fibrosis | 1 (0.3) | 0 (0) | 0 (0) | 0 (0) | 1 (5.3) | 0 (0) | .001 | |
Medium TSS | 8 (4–18) | 8 (6–14) | 8 (5–14) | 6 (4–11) | 7 (5–13) | 10 (8–18) | .000 | |
Stage III | ||||||||
Stable | 13 (3.6) | 3 (2.9) | 2 (4.3) | 4 (4.8) | 1 (5.3) | 3 (2.8) | .920 | |
Progression | 29 (8.0) | 9 (8.7) | 3 (6.4) | 0 (0) | 0 (0) | 17 (15.6) | .001 | |
Density | Scope | |||||||
↑ | – | 5 (17.2) | 1 (11.1) | 1 (33.3) | 0 (0) | 0 (0) | 3 (17.6) | .676 |
– | ↑ | 6 (20.7) | 5 (55.6) | 0 (0) | 0 (0) | 0 (0) | 1 (5.9) | .008 |
↑ | ↑ | 11 (37.9) | 1 (11.1) | 1 (33.3) | 0 (0) | 0 (0) | 9 (52.9) | .111 |
Appearance of new lesions | 7 (24.1) | 2 (22.2) | 1 (33.3) | 0 (0) | 0 (0) | 4 (23.5) | .923 | |
Disappearance in one area but appearance at another site | 14 (3.9) | 4 (3.9) | 0 (0) | 7 (8.4) | 0 (0) | 3 (2.8) | .105 | |
Absorption | 305 (84.5) | 87 (84.5) | 42 (89.4) | 72 (86.7) | 18 (94.7) | 86 (78.9) | .258 | |
Density | Scope | |||||||
↓ | – | 91 (29.8) | 15 (17.2) | 23 (54.8) | 27 (37.5) | 5 (27.8) | 21 (24.4) | .000 |
– | ↓ | 74 (24.3) | 39 (44.8) | 3 (7.1) | 14 (19.4) | 6 (33.3) | 12 (14.0) | .000 |
↓ | ↓ | 140 (45.9) | 33 (37.9) | 16 (38.1) | 31 (43.1) | 7 (38.9) | 53 (61.6) | .015 |
↓ | Slight ↑ | 0 | 0 | 0 | 0 | 0 | 0 | |
Appearance of pleural effusion | 2 (0.6) | 0 (0) | 1 (2.1) | 0 (0) | 0 (0) | 1 (0.9) | .475 | |
Appearance of fibrosis | 3 (0.8) | 1 (1.0) | 1 (2.1) | 0 (0) | 0 (0) | 1 (0.9) | .764 | |
Medium TSS | 3 (4–18) | 3 (6–14) | 3 (5–14) | 2 (0–3) | 2 (5–13) | 4 (8–18) | .000 |
GGO: ground-glass opacities; TSS: total severity score. ↑: increase; ↓: decrease.