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. 2021 Feb 11;16(2):e0246724. doi: 10.1371/journal.pone.0246724

Table 1. Preoperative variables.

Variable NON-ARD ARD OR (95% CI) p-value
(n = 90) (n = 111)
Mean age [years] 58.6 ± 13.1 62.6 ± 12.1 1.03 (1.00, 1.05) 0.031*
Male (ref. female) 56 [43] 75 [57] 1.27 (0.71, 2.3) 0.429
BMI [kg/m²] 26.9 ± 3.9 28.4 ± 4.3 1.09 (1.02, 1.17) 0.017*
ASA 3.9 ± 0.4 3.9 ± 0.5 1.05 (0.59, 1.89) 0.865
Arterial hypertension (ref. no) 67 [43] 89 [57] 1.39 (0.71, 2.70) 0.333
Coronary heart disease (ref. no) 8 [42] 11 [58] 1.13 (0.43, 2.93) 0.806
Aneurysm (ref. yes) 18 [51] 17 [49] 1.38 (0.67, 2.87) 0.385
AI (ref. yes) 39 [46] 45 [54] 1.12 (0.64, 1.97) 0.690
Pericardial disease (ref. no) 23 [42] 32 [58] 1.18 (0.63, 2.21) 0.605
Ischemia of the organ (ref. no) 2 [29] 5 [71] 2.08 (0.39, 10.96) 0.390
Ischemia of the limb (ref. no) 10 [38] 16 [62] 1.35 (0.58, 3.13) 0.489
COPD (ref. no) 4 [36] 7 [64] 1.45 (0.41, 5.11) 0.566
Nicotine (ref. no) 17 [38] 28 [62] 1.45 (0.73, 2.86) 0.285
Diabetes mellitus (ref. no) 4 [29] 10 [71] 2.13 (0.65, 7.03) 0.215
Chronic renal insufficiency (ref. yes) 5 [46] 6 [55] 1.03 (0.30, 3.49) 0.963
Neurological complication (ref. yes) 25 [46] 29 [54] 1.09 (0.58, 2.03) 0.793
CRP [mg/L] 5.6 (2.9–41.8) 6.6 (2.9–20.5) 1.00 (0.99, 1.01) 0.753
Leukocytes [/nL] 12.7 ± 4.0 12.7 ± 4.2 1.00 (0.93, 1.07) 0.995
CK [U/L] 104.0 (69.0–169.0) 100.0 (70.0–169.0) 1.00 (1.00, 1.00) 0.368

AI: aortic insufficiency; ARD: acute respiratory dysfunction; ASA: Score of the American Society of Anesthesiologists; BMI: body mass index; CK: creatine kinase; COPD: chronic obstructive pulmonary disease; CRP: C-reactive protein; Ischemia of the organ: heart, liver or kidney; Neurological complication: includes hemiplegia, paresis, seizure or stroke; Pericardial disease: includes effusion or tamponade.

All data are presented as the mean ± standard deviation, number [row-wise %] or median (IQR = interquartile range).

*: p < 0.05; p-value: logistic regression. Odds ratio (OR) and 95% confidence interval (95% CI).