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. 2021 Feb 11;16(2):e0246724. doi: 10.1371/journal.pone.0246724

Table 2. Intraoperative variables.

Variable NON-ARD ARD OR (95% CI) p-value
(n = 90) (n = 111)
Surgical procedure:
 Aortic root replacement 51 [50] 51 [50] reference
 Hemiarch replacement 29 [39] 45 [61] 1.55 (0.85, 2.85) 0.156
 Total arch replacement 10 [42] 14 [58] 1.40 (0.57, 3.44) 0.463
Duration of operation [min] 298 ± 64 297 ± 78 1.00 (1.00, 1.00) 0.945
CPB time [min] 172 ± 50 172 ± 58 1.00 (1.00, 1.01) 0.987
Cross-clamp time [min] 96 ± 34 99 ± 32 1.00 (0.99, 1.01) 0.620
Circulatory arrest time [min] 37 ± 18 40 ± 21 1.01 (0.99, 1.03) 0.395
Cerebral perfusion time [min] 32 ± 21 37 ± 22 1.01 (0.99, 1.03) 0.228
Reperfusion time [min] 61 ± 23 56 ± 20 1.01 (0.99, 1.03) 0.282
Hypothermia:
 deep ≤ 20°C 11 [58] 8 [42] reference
 moderate 20.1–28°C 61 [48] 66 [52] 1.49 (0.56, 3.94) 0.425
 mild 28.1–34°C 5 [56] 4 [44] 1.10 (0.22, 5.45) 0.907
Thiopental (ref. yes) 70 [46] 82 [54] 1.30 (0.67, 2.52) 0.432
Cortisone (ref. no) 26 [41] 37 [59] 1.23 (0.67, 2.25) 0.500
RBC [units] 2.7 ± 2.0 3.1 ± 2.1 1.08 (0.94, 1.24) 0.287
FFP [units] 6.1 ± 3.3 6.7 ± 3.9 1.05 (0.97, 1.14) 0.217
Platelets [units] 2.4 ± 0.9 2.5 ± 1.0 1.06 (0.78, 1.43) 0.713
PCC [units] 3658 ± 1834 3645 ± 1813 1.00 (1.00, 1.00) 0.959

ARD: acute respiratory dysfunction; Cortisone: e.g. prednisolone, dexamethasone; CPB time: cardiopulmonary bypass time; FFP: fresh frozen plasma; PCC: prothrombin complex concentrate; RBC: red blood cells.

All data are presented as the mean ± standard deviation or number [%]. *: p < 0.05; p-value: logistic regression. Odds ratio (OR) and 95% confidence interval (95% CI).