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. 2021 Feb 11;126(3):383–395. doi: 10.1038/s41437-021-00403-2

Fig. 3. Examples of loss-of-function (LoF) variants.

Fig. 3

Shown are those types caused by different kinds of mutations (SNP single nucleotide polymorphism, indel insertions and deletions), which vary in the kind of data needed to detect them (short/long read sequencing) and the predictability of their effect on gene function.