(a) 3-D geometry of aorta after segmentation and smoothing process, (b) time-dependent flow rates in the ascending and descending aorta obtained by CMR, (c) picture of a typical cuff device that is used in infants to measure mean pressure from one arm (right arm in this figure) non-invasively, (d) The model with inlet and outlet (O1, O2, O3, and O4) surfaces where the following boundary conditions are specified: flow rates at the inlet, O1, O2, and O3; and mean cuff pressure at O4 in this example, for steady simulations, (e) schematic of Windkessel model that is used at the outlet boundaries and resistances that are calculated using the mean pressures obtained by steady simulations, and (f) boundary conditions for the transient simulations