Table 1.
Clinical risk factors and CT-assessed candidate predictors of the patients.
| Characteristic | Training cohort | Validation cohort | ||||
|---|---|---|---|---|---|---|
| Relapse | Nonrelapse | P | Relapse | Nonrelapse | P | |
| Clinical risk factors | ||||||
| Patients | 26 (41.3%) | 37 (58.7%) | 5 (29.4%) | 12 (70.6%) | 0.271a | |
| Sex (no. [%]) | 0.941a | 0.825a | ||||
| Male | 15 (57.7%) | 21 (56.8%) | 4 (80.0%) | 9 (75.0%) | ||
| Female | 11 (42.3%) | 16 (43.2%) | 1 (20.0%) | 3 (25.0%) | ||
| Age (years) | 0.905a | 32.60 ± 20.80 | 30.50 ± 18.11 | 0.793a | ||
| <30 | 24 (80.0%) | 26 (78.8%) | 3 (60.0%) | 8 (66.7%) | ||
| ≥30 | 6 (20.0%) | 7 (21.2%) | 2 (40.0%) | 4 (33.3%) | ||
| Tumor location | 0.253a | 0.119a | ||||
| Long bone | 17 (65.4%) | 29 (78.4%) | 3 (60.0%) | 11 (91.7%) | ||
| Flat bone | 9 (34.6%) | 8 (21.6%) | 2 (40.0%) | 1 (8.3%) | ||
| ALP (alkaline phosphatase) level (IU/L) | 0.966a | 0.169a | ||||
| Normal | 17 (65.4%) | 24 (64.9%) | 2 (40.0%) | 9 (75.0%) | ||
| Abnormal | 9 (34.6%) | 13 (35.1%) | 3 (60.0%) | 3 (25.0%) | ||
| Hemoglobin level (mmol/L) | 0.031a | 0.149a | ||||
| Normal | 12 (46.2%) | 27 (73.0%) | 1 (20.0%) | 7 (58.3%) | ||
| Abnormal | 14 (53.8%) | 10 (27.0%) | 4 (80.0%) | 5 (41.7%) | ||
| CT-assessed candidate predictors | ||||||
| Tumor volume (mm3) | 281090.14 ± 306387.32 | 295712.47 ± 307695.10 | 0.856a | 1673453.67 ± 2236478.54 | 602010.56 ± 799571.06 | 0.300a |
| Surface | 105.76 ± 35.39 | 134.46 ± 85.98 | 0.105a | 377.23 ± 434.90 | 268.12 ± 272.45 | 0.493a |
| Size | 0.83 ± 0.66 | 0.82 ± 0.96 | 0.765a | 0.86 ± 0.03 | 0.86 ± 0.07 | 0.978a |
| Solidity | 0.69 ± 0.10 | 0.80 ± 0.16 | 0.003a | 0.80 ± 0.20 | 0.80 ± 0.18 | 0.947a |
| Eccentricity | 251.94 ± 180.57 | 317.44 ± 265.96 | 0.275a | 1169.81 ± 148.00 | 522.12 ± 578.42 | 0.343a |
| Compactness | 3.37 ± 2.04 | 0.9 ± 1.66 | 0.570a | 6.21 ± 4.78 | 4.43 ± 3.71 | 0.371a |
| Sphericity | 0.78 ± .0.17 | 0.68 ± .0.19 | 0.039a | 0.72 ± 0.25 | 0.77 ± 0.29 | 0.726a |
| Support vector regression | 1.20 ± 0.43 | 1.42 ± 0.74 | 0.169a | 0.98 ± 0.41 | 1.11 ± 0.39 | 0.529a |
| Irregularity | 1.33 ± 0.26 | 1.56 ± 0.40 | 0.011a | 1.55 ± 0.62 | 1.53 ± 0.69 | 0.941a |
| Joint invasion | 0.002a | 0.036a | ||||
| Yes | 17 (65.4%) | 10 (27.0%) | 4 (80.0%) | 3 (25.0%) | ||
| No | 9 (34.6%) | 27 (73.0%) | 1 (20.0%) | 9 (75.0%) | ||
| Pathologic fracture | 0.184a | 0.253a | ||||
| Yes | 4 (15.4%) | 2 (5.4%) | 0 (0.0%) | 0 (0.0%) | ||
| No | 22 (84.6%) | 35 (94.6%) | 5 (100.0%) | 12 (100.0%) | ||
∗ P value is less than 0.05. aChi-square test.