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. 2021 Feb 3;2021:8847140. doi: 10.1155/2021/8847140

Figure 1.

Figure 1

Analysis of oxidative stress state in SOD1(-/-) mice and wild-type mice. (a) SOD1(-/-) mice have smaller body size than age-matched wild-type mice (3 months). (b) Body weight measurement of SOD1(-/-) mice and wild-type mice at different time periods. (c) Serum ELISA shows successful deleting of SOD1 and total-SOD reduction in SOD1(-/-) male mice. (d, e) Serum ELISA of H2O2 and oxidative damage product (MDA) show obvious ROS accumulation in SOD1(-/-) male mice. (f) Serum ELISA of GSH-PX reductase shows no difference between SOD1(-/-) male mice and wild-type mice. Date are shown as mean ± SD (n = 5). P < 0.05; ∗∗P < 0.01.