Figure 1.

The effects of 17-DMAG on HT and neurological function in hyperglycemic MCAO rats. (a) 17-DMAG had no effects on blood glucose at the 4 time points. (b) Representative pictures of whole brain and TTC stained slices. 17-DMAG reduced hemorrhagic transformation following MCAO and decreased infarction volume. (c) Statistical analysis of blood volume in each group. 17-DMAG significantly reduced hyperglycemia-enhanced hemorrhagic volume at 24 h after MCAO. (d) Neurological function scoring at 24 h after MCAO. 17-DMAG significantly improved the neurological deficit at 24 h. ^∗p < 0.05 compared with sham group; ^#p < 0.05 compared with MCAO group. n = 5‐8 for each group.