Table 3.

Univariate regression analysis of the factors associated with MACCE outcomes in patients with coronary artery aneurysm

	HR (95% CI)	P value
Patient characteristics
Age (years)	1.051 (1.014 to 1.056)	0.01
Gender (male)	0.707 (0.504 to 0.993)	0.45
Diabetes mellitus	0.940 ((0.670 to 1.319)	0.72
Hypertension	0.664 (0.462 to 1.094)	0.07
Chronic heart failure	2.021 (1.471 to 2.775)	<0.001
Chronic kidney disease	1.685 (1.156 to 2.456)	0.007
Smoking history	1.025 (0.746 to 1.408)	0.88
Angina history	1.050 (0.750 to 1.468)	0.78
ACS on initial presentation	1.601 (1.051 to 2.441)	0.03
Coronary artery disease	1.450 (0.887 to 2.371)	0.14
H/O prior CABG	0.985 (0.707 to 1.373)	0.93
Peripheral vascular disease	0.959 (0.605 to 1.519)	0.85
Aneurysm anatomical details
Aneurysm location
LAD	1.036 (0.752 to 1.428)	0.83
LCA	0.893 (0.622 to 1.284)	0.54
RCA	0.894 (0.634 to 1.263)	0.53
LMA	1.584 (1.283 to 1.868)	<0.001
Atherosclerosis as cause	0.991 (0.572 to 1.717)	0.98
Aneurysm size	1.500 (0.665 to 3.379)	0.33
Aneurysm/vessel ratio	1.035 (0.810 to 1.322)	0.78
SYNTAX score	0.998 (0.958 to 1.040)	0.93
Interventions
CABG (ref: medical management)	0.684 (0.480 to 0.975)	0.03
PCI (ref: medical management)	0.895 (0.540 to 1.484)	0.67
DAPT use	1.038 ((0.741 to 1.454)	0.83
Warfarin use	0.973 (0.930 to 1.017)	0.22

ACS, acute coronary syndrome; CABG, coronary artery bypass grafting; DAPT, dual antiplatelet therapy; LAD, left anterior descending; LCA, left circumflex artery; LMA, left main artery; MACCE, major cardiovascular and cerebrovascular event; PCI, percutaneous coronary intervention; RCA, right coronary artery.