Table 3.

ROC curve parameters of quantitative parameters under two reference standards (at vessel level, n = 171)

Reference standard	Parameters	AUC	95% CI	Youden index	Optimal cut-off values	SN (%)	SP (%)	Z	P values
≥ 50%	sMBF	0.798	0.730–0.855	0.4618	1.48 ml/g/min	72.62	73.56	8.939	< 0.0001
	MFR	0.772	0.720–0.833	0.4433	1.77	85.70	58.6	7.649	< 0.0001
	RFR	0.685	0.609–0.753	0.2693	0.75	47.62	79.31	4.569	< 0.0001
≥ 75%	sMBF	0.801	0.733–0.858	0.5088	1.48 ml/g/min	83.64	67.24	8.563	< 0.0001
	MFR	0.770	0.699–0.831	0.4436	1.76	90.91	53.45	7.056	< 0.0001
	RFR	0.690	0.614–0.758	0.2773	0.75	52.73	75.00	4.480	< 0.0001