Table 1.
Patient demographic and diagnostic characteristics.
| Characteristic | Mean (SD) or Median [IQR] |
|---|---|
| Age – years | 52 (10) |
| Male sex – % | 71% |
| Race – % | |
| White | 57% |
| Black | 31% |
| Asian | 4% |
| Unknown/other | 8% |
| BMI – kg/m2 | 32 (6) |
| Systolic blood pressure at diagnosis – mmHg | 146 (21) |
| Diastolic blood pressure at diagnosis – mmHg | 88 (11) |
| Potassium at diagnosis – MEq/L | 3.5 (0.4) |
| # of blood pressure medications at 1st aldosterone/renin measurement | 3 (1) |
| # of aldosterone measurements | 3 (1) |
| Mean aldosterone – ng/dL | 20.3 (7.8) |
| Median plasma renin activity – ng/mL/h | 0.6 [0.3–0.6] |
| Median ARR – [(ng/dL)/(ng/mL/h)] | 47.5 [31.6–77.3] |
| Imaging findings – % | |
| Normal adrenal glands | 26% |
| Unilateral left adrenal nodule | 38% |
| Unilateral right adrenal nodule | 28% |
| Bilateral adrenal nodules | 8% |
| Lateralization at AVS (unstimulated, lateralization index ≥ 2) – % | |
| Bilateral disease | 25% |
| Unilateral disease | 75% |
| Lateralization at AVS (unstimulated, lateralization index ≥ 4) – % | |
| Bilateral disease | 39% |
| Unilateral disease | 61% |
| Treatment – % | |
| Medical therapy | 41% |
| Unilateral adrenalectomy or ablation | 59% |