Table 1.
Odorant | Mouse TAAR3 EC50 (M) |
Mouse TAAR4 EC50 (M) |
|||
---|---|---|---|---|---|
Primay Amines | |||||
in vitro | 1.0 x 10 −5 | c | n.r. | c | |
OSN | 1.5 x 10 −8 | a | 1.0 x 10−8 * | a | |
Glomerulus | 4.1 x 10−10 | b | 9.9 x 10 −9 | b | |
in vitro | 7.0 x 10 −6 | c | n.r. | c-d | |
OSN: | 2.7 x 10−7 | a | 7.7 x 10−10 | a | |
Glomerulus | 5.0 x 10−7* | a | 5.0 x 10−7* | a | |
in vitro | 4.0 x 10 −5 | c | 7.0 x 10−7 | c | |
OSN: | 1.0 x 10−6* | a | 1.0 x 10−12 | a | |
Glomerulus | 1.9 x 10−10 | b | 1.4 x 10−11 | b | |
Tertiay Amines | |||||
in vitro | n.r. | c-e | n.r. | c-e | |
OSN: | n.t | 1.0 x 10−8 * | a | ||
Glomerulus | 7.9 x 10 −7 | b | 4.7 x 10 −7 | b | |
in vitro | n.r. | c-e | n.r. | c-e | |
OSN: | 1.0 x 10−6* | a | 5.1 x 10−10 | a | |
Glomerulus | n.t. | n.t. | |||
Diamine | |||||
in vitro | n.r. | c | n.r. | c | |
OSN: | 1.0 x 10−6* | a | 1.0 x 10−8 * | a | |
Glomerulus | n.t. | n.t. |
Data is from the following studies:
responded at this concentration.
n.r. - no response. n.t. – not tested.