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Processes of cardiomyocyte metabolic gene expression, both normally and in AF. The fetal cardiomyocyte metabolic phenotype relies on glycolytic metabolism. As the cardiomyocytes differentiates, they switch to the mature cardiomyocyte metabolic phenotype of fatty acid metabolism. When cardiomyocytes experience pathological stress, they revert back to glycolytic metabolism. This occurs in certain stages of AF.
