Table 2.
Effect of Sex and Blood pressure status on Age, Hemodynamics, and Plasma Renin Angiotensin and Natriuretic Peptide Systems
| Variable | Normal (Mean ± SD) |
Hypertensive (Mean ± SD) |
Blood Pressure Status (p value) |
Sex (p value) |
Interaction (p value) |
|---|---|---|---|---|---|
| Age, (years) | |||||
| Women | 54 ± 8 | 61 ± 9 | |||
| Men | 55 ± 9 | 64 ± 8 | 0.012 | 0.4830 | 0.6989 |
| Systolic Blood Pressure, (mm Hg) | |||||
| Women | 117 ± 14 | 131 ± 16 | |||
| Men | 117 ± 13 | 136 ± 13 | 0.0002 | 0.5202 | 0.5342 |
| Pulse Pressure, (mm Hg) | |||||
| Women | 45 ± 18 | 56 ± 13 | |||
| Men | 43 ± 12 | 59 ± 10 | 0.0004 | 0.8148 | 0.5721 |
| Log Ang-(1–12), (ng/mL) | |||||
| Women | 2.02 ± 0.62 | 2.33 ± 0.63 | |||
| Men | 2.05 ± 0.55 | 2.51 ± 0.49 | 0.0216 | 0.5025 | 0.7265 |
| Plasma Renin Activity, (ng/mL/h) | |||||
| Women | 2.11 ± 2.57 | 9.17 ± 14.45 | |||
| Men | 2.30 ± 2.32 | 6.03 ± 3.22 | 0.0005 | 0.5481 | 0.7807 |
| Plasma NT-proBNP, (pg/mL) | |||||
| Women | 95.55 ± 81.54 | 141.00 ± 128.74 | |||
| Men | 36.30 ± 22.89 | 193.33 ± 146.55 | 0.0009 | 0.1682 | 0.0408 |
| Plasma cyclic GMP, (pmol/mL) | |||||
| Women | 7.56 ± 2.29 | 5.66 ± 2.31 | |||
| Men | 8.60 ± 2.79 | 10.04 ± 3.27 | 0.4722 | 0.0011 | 0.0283 |
Values are means ± SD. Lg, logarithm