Table 3.
Genes that were differentially expressed (n=9) in livers of female and male offspring from parents exposed to iAsa
| Gene (male livers) | Base mean | Log2 Fold change | p-value | Benjamini Hochberg adjusted p-value |
|---|---|---|---|---|
| G0/G1 switch gene 2 (G0s2) | 2364.91 | −1.820 | 7.91E-06 | 0.087 |
| Gene (female livers) | Base mean | Log2 Fold change | p-value | Benjamini Hochberg adjusted p-value |
| AarF domain containing kinase 5 (Adck5) | 550.79 | −0.74029 | 5.69E-07 | 0.006271 |
| Hydroxypyruvate isomerase (Hyi) | 1062.55 | −0.77357 | 2.42E-06 | 0.008925 |
| BTG3 associated nuclear protein (Banp) | 209.52 | −1.01104 | 2.43E-06 | 0.008925 |
| ATP-binding cassette subfamily A member 9 (Abca9) | 80.86 | 0.732965 | 1.49E-05 | 0.040947 |
| Cytochrome B-245 beta chain (Cybb) | 465.07 | 0.619609 | 1.86E-05 | 0.041049 |
| Ubiquitin-like modifier activating enzyme 6 (Uba6) | 112.97 | 0.788383 | 5.34E-05 | 0.097647 |
| ADP ribosylation factor Like GTPase 4D (Arl4d) | 349.28 | −0.71922 | 7.06E-05 | 0.097647 |
| Asparaginase (Aspg) | 3185.9 | −0.42721 | 7.09E-05 | 0.097647 |
a
Differentially expressed genes were identified based on Benjamini-Hochberg adjusted p-value <0.1.