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. 2021 Feb 11;11:3563. doi: 10.1038/s41598-021-82554-0

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Lipid inclusions and dystrophic changes in atrial appendage myocardial TCs in patients with AF. (a) Single lipid inclusions in the perinuclear zone of the TC cytoplasm. bar 1 µm. Insert—bar 2 µm. (b–d) The accumulation of multiple small and large lipid inclusions in the perinuclear zone of the TCs cytoplasm. bar 1 µm. (e) Myelin-like figures (Mf), rough endoplasmic reticulum (rER) and lipofuscin granules (Lf) in the TC cytoplasm. bar 2 µm. TEM. TC—telocyte, CMC—cardiomyocyte. L—lipid inclusions.