Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

editorial

. 2021 Jan 29;7:630498. doi: 10.3389/fmolb.2020.630498

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Gwizdek, Bardoni and Rage.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Schematic representation of the role of various RNPs in neurons. (A) RNPs biogenesis and shuttling between nucleus and cytoplasm. RNPs shuttle between nucleus and cytoplasm (1), they are involved in several RNA biogenesis steps processing including splicing (2) and nuclear export (3). They also undergo liquid-liquid phase transition regulated by m6A-mediated mRNA (4). (B) RNPs transport along dendrites or axons. Membraneless RNPs are composed of RBPs and RNAs associated with motor proteins to travel along microtubules. This association occurs either directly or through membrane-bound organelles. (C) RNA degradation. The process of mRNA degradation via miRISC is illustrated. (D) Local RNA translation. mRNA transported along axons is locally translated. The translation after transport along dendrites is illustrated in (C).