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. 2021 Jan 29;10:600980. doi: 10.3389/fonc.2020.600980

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Copyright © 2021 D’Agostino, Tombolan, Saggioro, Frasson, Rampazzo, Pellegrini, Favaretto, Biz, Ruggieri, Gamba, Bonvini, Aveic, Giovannoni and Pozzobon

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Xenogeneic samples with and without Matrigel^®. (A) Experimental strategy (3): cancer cells are injected with Matrigel^® or alone (B) Pictures of the masses produced with and without matrix support of the Matrigel^®. (C) Graph bars of the weight of the RMS xenogeneic masses with Matrigel^®, with BJ and with cancer cell alone. The weight of xeno RMS did not differ with Matrigel^® or with cancer cell alone. (D) Graph bars of the weight of the HT29 xenogeneic masses with Matrigel^®, with BJ and with cancer cell alone. HT29 xeno with BJ were heavier than with cancer cells only. HT29 only rarely gave rise to xeno masses. *p = 0.05. n.s., not significant.