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. 2020 Nov 12;36(2):404–412. doi: 10.1007/s11606-020-06331-x

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — Interaction between baseline alcohol dependence severity and WHO risk drinking level reduction achieved at the end of treatment in predicting quality of life outcomes at the 3-year follow-up assessment in COMBINE. a One-level RDL reduction predicting social quality of life (higher scores indicate greater quality of life). b Two-level RDL reduction predicting social quality of life (higher scores indicate greater quality of life). c Two-level RDL reduction predicting physical quality of life (higher scores indicate greater quality of life). Quality of life (QoL) was assessed by the World Health Organization (WHO) QOL–BREF scale, a measure of general QoL that covers physical, psychological, environmental, and social health domains. Higher scores indicate better QoL and Y-axis ranges based on observed data values.