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. 2020 Aug 7;14(1):75–87. doi: 10.1007/s12195-020-00643-y

Table 2.

Parameter sensitivity values.

Parameter Original Bolus autocrine (%) NP autocrine (%) Bolus diffusion NP diffusion
Vmax 1.00E−09 0.004 0.004 N/A* N/A*
km 1.00E−10 0.01 0.01 No impact** No impact**
Dc 1.00E−11 0.10 0.10 10.00% 10.00%
kdeg 0.000406 0.002 0.002 5.00% 5.00%
ka 50 0.008 0.008 No impact** No impact**
ke 0.00105 0.005 0.005 No impact** No impact**
Vr 3.50E−13 0.006 0.006 No impact** No impact**
kr 1.00E−10 0.009 0.009 No impact** No impact**
vrc 1.00E−16 5.00 5.00 No impact** No impact**
crt 1.00E−09 0.01 0.01  No impact** No impact**
blc 1.00E−06 0.10 0.10 5.00% 5.00%

*Parameter is set to zero for model

**Parameter is multiplied by zero or dependent on unchanging parameter