Table 2.
Parameter | Original | Bolus autocrine (%) | NP autocrine (%) | Bolus diffusion | NP diffusion |
---|---|---|---|---|---|
Vmax | 1.00E−09 | 0.004 | 0.004 | N/A* | N/A* |
km | 1.00E−10 | 0.01 | 0.01 | No impact** | No impact** |
Dc | 1.00E−11 | 0.10 | 0.10 | 10.00% | 10.00% |
kdeg | 0.000406 | 0.002 | 0.002 | 5.00% | 5.00% |
ka | 50 | 0.008 | 0.008 | No impact** | No impact** |
ke | 0.00105 | 0.005 | 0.005 | No impact** | No impact** |
Vr | 3.50E−13 | 0.006 | 0.006 | No impact** | No impact** |
kr | 1.00E−10 | 0.009 | 0.009 | No impact** | No impact** |
vrc | 1.00E−16 | 5.00 | 5.00 | No impact** | No impact** |
crt | 1.00E−09 | 0.01 | 0.01 | No impact** | No impact** |
blc | 1.00E−06 | 0.10 | 0.10 | 5.00% | 5.00% |
*Parameter is set to zero for model
**Parameter is multiplied by zero or dependent on unchanging parameter