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. 2021 Mar 5;31(3):172–179. doi: 10.2188/jea.JE20190296

Table 4. Seven identified SNPs associated with the current BMI adjusted for total energy intake.

SNP Candidate
gene(s)
Current BMI

Adjusted modela Adjusted model + total energyd/weighte

βb P-valuec βb P-valuec
rs4409766 BORCS7-ASMT 0.181 4.96E-05 0.036 2.93E-01
rs11030100 BDNF-AS −0.199 1.68E-06 −0.082 8.95E-03
rs6265 BDNF −0.203 1.00E-06 −0.071 2.26E-02
rs11030104 BDNF-AS −0.203 1.01E-06 −0.067 3.18E-02
rs1421085 FTO 0.335 1.24E-10 0.174 8.02E-06
rs11642015 FTO 0.334 7.36E-11 0.173 8.41E-06
rs1558902 FTO 0.331 8.65E-11 0.174 7.69E-06

BMI, body mass index; SNP, single nucleotide polymorphism.

aAdjusted models were adjusted for age (continuous), age-squared (continuous), sex (male or female), birth year (continuous), and the top 5 principal components (continuous).

bAlternative alleles were treated as effect alleles.

cSignificant P-values (P ≤ 1.77E-04) are shown in bold.

dTotal energy was estimated using a self-reported food frequency questionnaire.

eWeight indicates self-reported current weight.