Figure 1.

NP Transplant Does Not Affect Systemic Cytokines Induced by Hemorrhagic Shock

Mice were subjected to either hemorrhagic shock or sham procedure, and then received transplant with or without NPs. At (A) 90 min or (B) 24 h after resuscitation, serum was collected and analyzed for the concentration of IL-6, CXCL1, TNFα, IL-1β, IL-10, G-CSF, and GM-CSF. Data were acquired across at least three independent experiments, with duplicate measures of each sample/cytokine. Data are expressed as means ± SEM. Data were fit to a lognormal distribution, analyzed by GLMs, and the Holms test was used to adjust for multiple comparisons. ^∗p < 0.05, ^∗∗p < 0.01, ^∗∗∗p < 0.001.