Table 2.
Demographic and clinical characteristics of the clinical cohort from which researchers recruited study respondents
| Characteristic | Value |
|---|---|
| Female, % | 88 |
| African-American, % | 57.7 |
| dsDNA-positive, % | 67.8 |
| Prednisone, % | 46.8 |
| Prednisone dose, mg, mean (s.d.) | 16.14 (14.46) |
| S2K RI-50 score, mean (s.d.) | 5.14 (5.74) |
| Age, years, mean (s.d.) | 41.7 (13.3) |
| Blood iC3b, µg/ml, mean (range) | 4.27 (0.7–21.0) |
| Blood iC3b/C3 ratio, µg/mg, mean (range) | 4.49 (0.66–68.95) |
Data are inclusive of 323 subjects with classified SLE. S2K RI-50: Systemic Lupus Erythematosus Disease Activity Index 2000 Responder Index-50; iC3b: iC3b is a protein generated with complement activation, a process that is central to the inflammatory nature of SLE; iC3b/C3 ratio: iC3b/C3 ratio is the proportion between iC3b levels and C3 levels. C3, when activated and broken down, generates iC3b.