Table 4.

Summary of meta-analyses.

SNP	Ethnicity	Studies	Genetic model	OR	95% CI	p Value	Model	I2%	Begg’s test p Value
rs1801133	Overall	20	T vs C	1.12	0.98–1.28	0.094	R	64.3	0.347
			TT + TC vs CC	1.14	0.96–1.36	0.111	R	53.5	0.417
			TT vs TC + CC	1.15	0.89–1.48	0.271	R	53.9	0.721
	European	12	T vs C	1.12	0.94–1.37	0.190	R	53.7	0.631
			TT + TC vs CC	1.17	1.11–1.36	0.036	F	13.8	0.537
			TT vs TC + CC	1.12	0.78–1.61	0.407	R	56.9	0.537
	Asian	6	T vs C	1.19	0.90–1.58	0.211	R	73.2	0.260
			TT + TC vs CC	1.22	0.87–1.72	0.240	R	70.4	0.260
			TT vs TC + CC	0.95	0.72–1.27	0.750	F	38.7	0.060
	Mexican Mestizos	2	T vs C	1.05	0.50–2.19	0.894	R	90.9	0.999
			TT + TC vs CC	0.95	0.32–2.72	0.926	R	87.5	0.999
			TT vs TC + CC	1.14	0.46–2.83	0.769	R	84.7	0.999
rs1491942	Overall	6	C vs G	1.25	1.10–1.14	0.012	R	81.7	0.548
	European	4	C vs G	1.14	1.07–1.22	<0.001	F	26.1	0.308
	Asian	2	C vs G	1.43	0.85–2.42	0.181	R	95.8	0.999
	Mexican Mestizos	1	C vs G	1.69	1.29–2.32	0.203	R	ND	ND

R random effects model, F fixed-effects model.