Table 3.
Diagnostic accuracy of urogenital cytology for gynaecological cancer detection.
| Test performance | Vaginal cytology | Urine cytology | Combined cytologya |
|---|---|---|---|
| % (95% CI) | % (95% CI) | % (95% CI) | |
| Sensitivity | 89.6 (82.2, 94.7) | 72.0 (62.1, 80.5) | 91.7 (84.9, 96.2) |
| Specificity | 88.7 (80.6, 94.2) | 94.9 (88.4, 98.3) | 88.8 (81.2, 94.1) |
| Positive likelihood ratio | 7.90 (4.5, 13.9) | 13.9 (5.3, 33.1) | 8.2 (4.8, 14.0) |
| Negative likelihood ratio | 0.12 (0.07, 0.21) | 0.30 (0.21, 0.41) | 0.09 (0.05, 0.17) |
| Disease prevalence | 52.2 (45.1, 59.3) | 50.8 (43.6, 57.9) | 50.5 (43.6, 57.3) |
| Positive predictive value | 89.7 (83.1, 93.8) | 93.5 (85.9, 97.5) | 89.3 (83.0, 93.4) |
| Negative predictive value | 88.7 (81.7, 93.2) | 76.7 (70.5, 81.9) | 91.4 (84.9, 95.2) |
| Diagnostic accuracy | 89.2 (84.1, 93.1) | 83.2 (77.3, 88.2) | 90.3 (85.5, 93.9) |
95% CI, 95% confidence intervals.
aEither vaginal or urine cytology positive.