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. 2021 Feb 11;4:186. doi: 10.1038/s42003-021-01716-y

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — a KEGG enrichment analysis of the DEGs of L. vannamei (Lva) and F. chinensis (Fch). Only the pathways with significantly enriched DEGs (p < 0.05) are shown on the heatmap. NA indicates no DEGs identified in related pathways. b Expression patterns of the DEGs in different pathways. The number of DEGs and their corresponding expression patterns are shown in the yellow box at right. c Differentially regulated metabolites in penaeid shrimp under low-salinity stress. Metabolite levels were compared between the two shrimp species, and the metabolites were divided into four groups, namely, those differentially regulated in only L. vannamei (yellow background), those differentially regulated in only F. chinensis (orange background), those up- or downregulated consistently in both shrimp species (light blue background), and those with different regulation patterns between the two shrimp species (green background). A white background indicates no significant difference. d Correlations between DEGs and differentially regulated metabolites in the pathway of glycine, serine, and threonine metabolism in both the L. vannamei and F. chinensis genomes. e SSR contents in all identified peaks at 3% and 30% salinity and only the differential peaks (3% vs. 30%) identified by ATAC-seq. The differential peaks were identified according to various p values from differential analyses of ATAC-seq. f ATAC peak distribution and structure comparison of the glyA gene in both L. vannamei and F. chinensis. The brown lines indicate orthologous regions of the differential peaks in the genes.