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. 2021 Feb 11;11:3611. doi: 10.1038/s41598-021-83120-4

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Correlation between the IRGPs signature and clinical characteristics. (A) Heat map for the distribution of clinicopathological features between high- and low- risk group. (B) The difference of risk score between different gender, (C) between patients with and without radiotherapy, (D) among different TNM grades, (E) among different tumor size, (F) between with and without lymph node metastasis, (G) between with and without distance metastasis. *P < 0.05, **P < 0.01, ***P < 0.001.