TABLE 3.
Imputability and severity designations of transfusion-related adverse reactions reported to the NHSN Hemovigilance Module, United States, 2010 to 2012
| Adverse reaction | Number | (%) | Imputability (n = 5136) |
Severity (n = 5136) |
||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Definite | Probable | Possible | Nonsevere | Severe | Life-threatening | Fatal | Not determined | |||
| Allergic | 2406 | (46.8) | 1481 | 735 | 190 | 2232 | 160 | 12 | 0 | 2 |
| FNHTR | 1853 | (36.1) | 670 | 598 | 585 | 1829 | 18 | 0 | 0 | 6 |
| DSTR | 321 | (6.3) | 321 | 302 | 3 | 0 | 0 | 16 | ||
| TACO | 196 | (3.8) | 67 | 85 | 44 | 123 | 59 | 13 | 0 | 1 |
| Hypotensive | 136 | (2.6) | 32 | 55 | 49 | 102 | 28 | 6 | 0 | 0 |
| DHTR | 90 | (1.8) | 67 | 16 | 7 | 69 | 17 | 0 | 0 | 4 |
| TAD | 72 | (1.4) | 21 | 24 | 27 | 54 | 11 | 6 | 0 | 1 |
| TRALI | 26 | (0.5) | 6 | 20 | 4 | 15 | 4 | 3 | 0 | |
| AHTR | 24 | (0.5) | 15 | 7 | 2 | 12 | 10 | 2 | 0 | 0 |
| TTI | 12 | (0.2) | 6 | 2 | 4 | 3 | 8 | 0 | 1 | 0 |
| Total (%) | 5136 | (100) | 2686 (52.3) | 1522 (29.6) | 928 (18.1) | 4730 (92.1) | 329 (6.4) | 43 (0.8) | 4 (0.1) | 30 (0.6) |
AHTR = acute hemolytic transfusion reaction; DHTR = delayed hemolytic transfusion reaction; DSTR = delayed serologic transfusion reaction; FNHTR = febrile nonhemolytic transfusion reaction; TACO = transfusion-associated circulatory overload; TAD = transfusion-associated dyspnea; TRALI = transfusion-related acute lung injury; TTI = transfusion-transmitted infection.